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. Author manuscript; available in PMC: 2022 Mar 22.
Published in final edited form as: RSC Adv. 2019 Aug 12;9(43):25039–25047. doi: 10.1039/c9ra04037d

Figure 2.

Figure 2.

Internalization of TiO2 NPs observed by TEM. A549 cells were incubated with TiO2 NPs (800 μg/mL, T-25 flasks). A. Cold-binding (4°C for 10 min). B. 1 hr incubation at 37°C. C. 24 hr incubation at 37°C. In addition to internalization into large (3-5 μm) vacuoles, the TiO2 NPs were also observed associated with myelin-like figures (Figure S2).