Table 3.
Greater activation in OCD patients than controls during late eyeblink suppression.
| Label | Harvard-Oxford Parcel | BA | k | x | y | z |
|---|---|---|---|---|---|---|
| Parietal | ||||||
| Inferior parietal lobule | Superior Parietal Lobule (R) | 40 | 63 | 32 | −46 | 38 |
| Mid cingulate | Cingulate Gyrus, Posterior (R) | 31 | 32 | 14 | −46 | 36 |
| Precuneus/cuneus | Precuneous Cortex (R) | 31 | 106 | 14 | −62 | 16 |
| Precuneus/mid cingulate | Precuneous Cortex (R) | 31 | 43 | 14 | −46 | 40 |
| Calcarine/lingual gyrus/posterior cingulate | Precuneous Cortex (R) | 29 | 23 | 10 | −54 | 4 |
| Precuneus | Precuneous Cortex (L) | 7 | 22 | −16 | −72 | 34 |
| Precuneus/cuneus | Precuneous Cortex (R) | 7 | 234 | 16 | −70 | 28 |
| Occipital | ||||||
| Calcarine/cuneus/posterior cingulate | Intracalcarine Cortex (L) | 17, 18, 23, 30 | 225 | −16 | −68 | 2 |
| Cuneus | Intracalcarine Cortex (L) | 17, 18 | 31 | −2 | −90 | −4 |
| Calcarine/cuneus/posterior cingulate | Intracalcarine Cortex (R) | 17, 18, 30 | 289 | 8 | −84 | 0 |
| Calcarine/posterior cingulate | Supracalcarine Cortex (R) | 31 | 39 | 22 | −64 | 12 |
| Cuneus/calcarine | Supracalcarine Cortex (R) | 18, 31 | 30 | 4 | −88 | 8 |
| Cuneus/precuneus | Cuneal Cortex (L) | 7, 18, 19, 31 | 228 | −14 | −76 | 18 |
| Cuneus/precuneus | Cuneal Cortex (R) | 7, 18, 19, 31 | 360 | 2 | −88 | 14 |
| Lingual gyrus/cuneus/parahippocampal gyrus | Lingual Gyrus (L) | 18, 30 | 114 | −32 | −42 | −8 |
| Lingual gyrus/calcarine | Lingual Gyrus (L) | 18 | 29 | −4 | −86 | −14 |
| Lingual gyrus/calcarine | Lingual Gyrus (R) | 18 | 162 | 10 | −90 | −12 |
| Lingual gyrus/parahippocampal gyrus | Lingual Gyrus (R) | 18, 19, 30 | 93 | 16 | −50 | −4 |
| Middle occipital gyrus/precuneus/superior occipital gyrus | Lateral Occipital Cortex, Superior (L) | 7, 39 | 96 | −26 | −66 | 30 |
| Precuneus/superior occipital gyrus/middle occipital gyrus/angular gyrus | Lateral Occipital Cortex, Superior (R) | 7, 39 | 197 | 28 | −72 | 24 |
| Cuneus/middle occipital gyrus | Occipital Pole (L) | 17, 18, 19 | 251 | −4 | −92 | −2 |
| Cuneus/calcarine/middle occipital gyrus | Occipital Pole (R) | 18 | 41 | 2 | −90 | 4 |
Labels are derived from the Automated Anatomical Labeling and Talairach Daemon databases as provided through xjview (v. 9.6, http://www.alivelearn.net/xjview). Harvard-Oxford Atlas parcels are provided through the ‘conn’ tool (Whitfield-Gabrieli & Nieto-Castanon, 2012). Within a given cluster, labels are listed in descending order based on the proportion of voxels within the cluster assigned to that label. Some clusters span across two different lobes; for these clusters, lobe assignment is based on the lobe with the greatest proportion of voxels in that cluster.
BA=Brodmann’s areas; k=cluster extent; R=right, L=left; coordinates are in MNI space. Only clusters with 20 or more contiguous voxels are listed. Parcels represent subdivisions from clusters corrected for a whole-brain family-wise error rate of p<0.05 using permutation testing.