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. Author manuscript; available in PMC: 2020 Jan 30.
Published in final edited form as: Cell Mol Life Sci. 2016 Oct 6;74(6):983–1000. doi: 10.1007/s00018-016-2373-0

Figure 3. Physiology of the Failing Heart.

Figure 3

An excess load chronically imposed the heart results in failure to satisfy the metabolic requirements of end organ tissues, afflicting the patient with pulmonary edema and excess fluid and sodium retention. *RAAS = Renin-Angiotensin-Aldosterone System