Table 3.

pQCT and DXA Outcomes in Participants With SSNS Compared With Controls

Z-score	SSNS	p	SSNS adjusted for muscle Z-score	p	SSNS adjusted for BMI Z-score	p
pQCT
TrabBMD	−0.60 (−0.89, −0.31)	<0.0001	−0.69 (−0.97, −0.41)	<0.0001	−0.69 (−0.98, −0.41)	<0.0001
CortBMD	1.17 (0.89, 1.45)	<0.0001	1.17 (0.89, 1.45)	<0.0001	1.18 (0.90, 1.45)	<0.0001
CortBMC	0.60 (0.32, 0.87)	<0.0001	0.38 (0.17, 0.59)	<0.001	0.45 (0.20, 0.71)	<0.001
Cortical CSA	0.37 (0.09, 0.66)	0.01	0.14 (−0.08, 0.35)	0.20	0.22 (−0.04, 0.48)	0.10
Zp	0.07 (−0.20, 0.33)	0.62	−0.15 (−0.35, 0.06)	0.16	−0.10 (−0.34, 0.13)	0.39
SSIp	0.29 (0.02, 0.56)	0.04	0.07 (−0.14, 0.29)	0.51	0.14 (−0.11, 0.39)	0.28
Muscle CSA	0.34 (0.08, 0.61)	0.01
Fat CSA	0.56 (0.27, 0.84)	<0.001
DXA
PA areal BMD	−0.08 (−0.37, 0.20)	0.56	−0.16 (−0.44, 0.11)	0.24	−0.23 (−0.50, 0.04)	0.09
WA BMD	−0.45 (−0.75, −0.16)	0.002	−0.52 (−0.81, −0.23)	0.001	−0.53 (−0.82, −0.24)	<0.001

The sex- and race-specific Z-scores are presented with the 95% CIs.

The Z-scores for the pQCT vBMD and DXA BMD outcomes were generated relative to age. The remaining pQCT cortical, muscle, and fat Z-scores were generated relative to tibia length and then adjusted for age.