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. Author manuscript; available in PMC: 2015 Apr 20.
Published in final edited form as: Neurotherapeutics. 2009 Apr;6(2):372–380. doi: 10.1016/j.nurt.2009.01.001

Table 1. Anticonvulsant profile of NAX 5055.

Seizure Model ED50 (mg/kg i.p.) PIa
Corneal Kindling 0.65 ∼30
Audiogenic Seizures 3.2 ∼7
Maximal Electroshock Inactive at 20 mg/kg <1
s.c. Pentylenetetrazol 25% at 20 mg/kg <1
a

PI, protective index; i.e., TD50 (21 mg/kg)/ED50

s.c., subcutaneous injection