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Hippocampal CA3 cell density. Representative Nissl-stained coronal sections of treatment groups. A. Sham-injured animal: many healthy neurons, with pale, plump nuclei and prominent nucleoli. B. Vehicle-treated: striking neuronal loss. C. Free tPA treated: intermediate neuronal loss. D. RBC/tPA treated: modest neuronal loss. Original magnification 20x; bar = 50 μm.
tPA: tissue plasminogen activator
