Table 2. Activated brain regions.
| Brain region | Peak MNI coordinates | Extent (mm3) | P value | Max T | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| Viewing pictures or scrambled pictures | ||||||
| Bilateral occipital cortex (all but the most dorsal parts), extending to posterior ITG and posterior fusiform gyrus | -6 | -96 | -6 | 217280 | <0.0001 | 23.52 |
| Naming pictures | ||||||
| Left frontal, temporal and subcortical regions | 110096 | <0.0001 | ||||
| Precentral gyrus | -40 | -8 | 26 | 14.56 | ||
| Posterior IFG, pars opercularis and triangularis | -54 | 12 | 20 | 8.63 | ||
| STS | -56 | -28 | 0 | 7.97 | ||
| Left basal ganglia | -16 | -4 | 14 | 11.98 | ||
| Thalamus | -4 | -12 | 6 | 14.43 | ||
| Right precentral gyrus and STG | 31112 | <0.0001 | ||||
| Central sulcus | 40 | -8 | 30 | 10.18 | ||
| STG | 66 | -24 | 6 | 7.69 | ||
| Pre-SMA, anterior SMA, and dorsal mid Cingulate | -6 | 6 | 56 | 17464 | <0.0001 | 10.91 |
| Left cerebellum and posterior ITG | -10 | -52 | -8 | 16216 | <0.0001 | 7.05 |
| Cerebellum | -12 | -64 | -22 | |||
| Posterior ITG | -50 | -56 | -18 | 5.58 | ||
| Right cerebellum | 40 | -58 | -26 | 9968 | <0.0001 | 7.95 |
| Correlations with familiarity (more signal for less familiar items) | ||||||
| Right fusiform gyrus and ventral occipital cortex | 31176 | <0.0001 | ||||
| Fusiform gyrus | 36 | -46 | -28 | 12.29 | ||
| Occipital cortex | 22 | -92 | -2 | 11.56 | ||
| Left posterior fusiform gyrus and middle occipital gyrus | -50 | -80 | 4 | 5448 | 0.0016 | 5.17 |
| Midbrain and left superior cerebellar peduncle | -14 | -54 | -32 | 4064 | 0.0067 | 6.95 |
| Left posterior fusiform gyrus | -38 | -54 | -22 | 2488 | 0.051 | 7.86 |
| Correlations with frequency (more signal for less frequent items) | ||||||
| Left SMG | -64 | -34 | 24 | 3280 | 0.017 | 8.29 |
| Left posterior ITG | -44 | -68 | -10 | 2752 | 0.035 | 5.33 |
| Correlations with length (more signal for longer items) | ||||||
| Cerebellum | 12 | -70 | -10 | 12624 | <0.0001 | 6.19 |
| Left Heschl's Gyrus, STG and STS | -54 | -2 | -16 | 4824 | 0.0030 | 6.22 |
| Left middle occipital gyrus, superior part | -38 | -68 | 50 | 3824 | 0.0088 | 6.19 |
| Left SFS and SMA | 2944 | 0.027 | ||||
| SMA | -6 | 2 | 46 | 7.02 | ||
| Superior frontal sulcus | -26 | 10 | 60 | 5.15 | ||
| Right Heschl's Gyrus | 58 | -10 | -4 | 2528 | 0.048 | 5.24 |
| Correlations with reaction time (more signal for longer RTs) | ||||||
| Bilateral occipital cortex, fusiform gyrus and cerebellum, and left posterior ITG | 58032 | <0.0001 | ||||
| Lingual gyrus | -4 | -80 | -12 | 10.83 | ||
| Left fusiform gyrus | -28 | -54 | -22 | 6.63 | ||
| Right fusiform gyrus | 26 | -52 | -22 | 6.34 | ||
| Left posterior ITG | -44 | -58 | -18 | 6.64 | ||
| Left cerebellum | -44 | -64 | -36 | 5.55 | ||
| Right cerebellum | 28 | -66 | -32 | 9.91 | ||
| Left posterior IFG, inferior precentral sulcus and precentral gyrus | 25096 | <0.0001 | ||||
| Ventral pars opercularis | -56 | 8 | 2 | 10.12 | ||
| Pars triangularis | -58 | 18 | 22 | 8.03 | ||
| Pars orbitalis | -44 | 34 | -8 | 4.02 | ||
| Inferior precentral sulcus | -42 | 4 | 28 | 8.82 | ||
| Precentral gyrus | -44 | 4 | 48 | 5.02 | ||
| Pre-SMA and dorsal mid Cingulate | 13904 | <0.0001 | ||||
| Mid Cingulate | -6 | 14 | 40 | 9.36 | ||
| Pre-SMA | -2 | 14 | 58 | 7.95 | ||
| Right anterior insula | 38 | 18 | -2 | 6176 | 0.0009 | 7.75 |
| Left middle occipital gyrus | -32 | -86 | 14 | 5288 | 0.0019 | 7.34 |
| Right middle occipital gyrus | 38 | -80 | 8 | 3816 | 0.0089 | 7.63 |
| Thalamus | -2 | -6 | 2 | 3624 | 0.011 | 7.55 |
| Left mid STS | -58 | -28 | -4 | 2128 | 0.089 | 7.40 |
Brain regions significantly activated in contrasts of interest. For large clusters, prominent local maxima are listed separately (indented).