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. Author manuscript; available in PMC: 2006 Sep 28.
Published in final edited form as: Cell Mol Life Sci. 2005 Jul;62(13):1434–1447. doi: 10.1007/s00018-005-4523-7

Figure 2.

Figure 2

(A) Translocation, t(5;11)(q13.3;p15.1), associated with KTS. Breakages occur on one of the chromosomes 5 and 11 at the bands q13.3 (red) and p15.1 (blue), respectively. Broken pieces are exchanged between chromosomes involved, resulting in the formation of two abnormal chromosomes, derivative chromosomes 5 and 11 (Chr, chromosome; Der, derivative). (B) AGGF1 at the 5q13.3 breakpoint. The 5q13.3 breakpoint is 1644 bp upstream from the start codon (ATG) of AGGF1. AGGF1 contains 14 exons. (C) AGGF1 protein structure. There are four putative functional domains; coiled-coil, OCRE (octamer repeat), FHA (Forkhead-associated) and G-patch domains.