Table 1.
Diagnosis and clinical information of patients from whom the six RCC cell lines were established
| Parameter | Cell line designation | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| RCC52 | RCC98 | HH050 | HH244 | HH332 | HOKN-9 | |||||||
| Histopathologic type | Sarcomatoidb (with residual clear cell carcinoma found) | Chromophobe cell carcinoma | Papillary renal cell carcinoma | Tubular carcinoma | Clear cell carcinoma | Clear cell carcinoma | ||||||
| Fulman grade | 3 | 2 | –a | – | – | – | ||||||
| Stage | IIIb | II | – | – | – | – | ||||||
| Clinical status | DOD | DOD | DOD | DOD | DOD | DOD | ||||||
| Genotype of HLA class Ic | A2 | A11 | A2 | A24 | A2 | A3 | A1 | A24 | A24 | A29 | A2 | A24 (9) |
| B46 | B60 (40) | B35 | B46 | B62 | B35 | B8 | B35 | B51 | B58 | B35 | B46 | |
| Cw1 | Cw7 | Cw1 | Cw9 (3) | C3 | C4 | C4 | C7 | C7 | C14 | C1 | C3 | |
| Initiator(s) of cell line | C-K. Chuang and S-K. Liao, Taiwan | C-K. Chung and S-K. Liao, Taiwan | S. K. Nayak, USA | S. K. Nayak, USA | S. K. Nayak, USA | Y. Yoshida and K. Hasumi, Japan | ||||||
DOD died of disease
a
Unknown
b
Original diagnosis was sarcomatoid RCC, and after careful evaluation of tumor sections in this study it was found to be a mixture of sarcomatoid and clear cell RCC with a dominant sarcomatoid element. Of note is that the RCC52 cell line established in vitro composed exclusively of sarcomaoid cells
c
Results were generated from this study (see text)