Table 4.
A list of novel potential c-Src kinase substrates identified in this study with no prior known involvement in PDGF receptor signaling pathway
| Accession # | Protein | Fold increase (medium/light ± SD*) |
Fold increase (heavy/light ± SD*) |
|
|---|---|---|---|---|
| 1 | NP_031969 | Eps15 | 2.5 ± 0.4 | 1.0 ± 0.3 |
| 2 | NP_035718 | Tripartite motif protein 28 | 2.4 | 1.0 |
| 3 | NP_001028465 | UAP1 like-1 | 2 | 1.4 |
| 4 | NP_035853 | Xanthine dehydrogenase | 1.8 | 0.9 |
| 5 | NP_035449 | Seryl-aminoacyl-tRNA synthetase 1 | 1.7 | 1.0 |
| 6 | NP_033924 | Calpain 2 | 1.5 ± 0.2 | 1.0 ± 0.08 |
| 7 | NP_919323 | Unc-84 homolog | 1.5 | 0.8 |
| 8 | NP_034611 | Heat shock protein 9A | 1.4 ± 0.07 | 0.9 ± 0.3 |
| 9 | NP_149065 | Threonyl-tRNA synthetase | 1.4 | 0.9 |
| 10 | NP_058017 | Stress-induced phosphoprotein 1 | 1.3 ± 0.06 | 1.0 ± 0.01 |
| 11 | NP_001028472 | Guanine monophosphate synthetase | 1.3 | 0.9 |
| 12 | NP_031933 | eEF 2 | 1.3 ± 0.1 | 0.9 ± 0.2 |
| 13 | NP_031623 | Calnexin | 1.3 ± 0.1 | 0.9 ± 0.1 |
| 14 | NP_598798 | ATP citrate lyase | 1.2 ± 0.05 | 0.8 ± 0.01 |
| 15 | NP_034607 | Heat shock protein 1 (chaperonin) | 1.3 ± 0.05 | 0.9 ± 0.1 |
*
SD: Standard deviation calculated from the ratio of peptides quantitated by SILAC.