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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Hum Brain Mapp. 2010 Apr;31(4):499–514. doi: 10.1002/hbm.20882

Figure 3.

Figure 3

AD (n = 24) versus controls (n = 35) scanned at 3 T. The top panels reflect the mean level of atrophy as a percentage reduction in volume over one year (%/year) beyond that found in controls (in other words, the mean control rate of atrophy has been subtracted out). Blue colors represent volume reduction while red colors represent volume expansion. Corresponding color-coded P maps show where atrophy in AD is significantly faster than in controls (bottom panels). The majority of the brain shows faster change in AD than controls. It is important to note that the regions of atrophy shown in this figure represent excess atrophy over and above age-related atrophy. [Color figure can be viewed in the online issue, which is available at www.interscience.wiley.com.]