. Author manuscript; available in PMC: 2009 Oct 19.

Published in final edited form as: Hum Hered. 2008 Dec 12;67(2):88–103. doi: 10.1159/000179557

Table 6.

Relative efficiency of parameter estimates under both the gene-environment interaction and gene-gene interaction models for case-parents triads . The results are based on 1000 simulated datasets, each consist of 500 case-parents triads.

Scheme	β₁ = 0:405	β₂ = 0:405	β₃ = 0:405	β₄ = 0:693	β₅ = 1:100
Gene-Environment Interaction Model
Full	1.00	1.00	1.00	-	1.00
1 counter	0.95	0.90	0.94	-	0.96
5 counter	0.98	0.96	0.98	-	0.99
9 counter	0.98	0.97	1.00	-	1.00
1 random	0.52	0.51	0.48	-	0.48
5 random	0.77	0.71	0.75	-	0.80
9 random	0.85	0.84	0.84	-	0.86
Gene-Gene Interaction Model
Full	1.00	1.00	1.00	-	1.00
1 counter	0.90	0.93	0.88	-	0.46
5 counter	0.97	0.97	0.94	-	0.77
9 counter	0.99	0.99	0.96	-	0.95
1 random	0.47	0.49	0.49	-	0.40
5 random	0.75	0.80	0.73	-	0.72
9 random	0.87	0.82	0.81	-	0.79