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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Eur J Hum Genet. 2009 Jan 14;17(6):831–839. doi: 10.1038/ejhg.2008.250

Table 4.

Number of transmitted or non-transmitted associated alleles to 297 CL/P cases (all populations combined)a from TAT and estimated odds ratios, and parent-of-origin likelihood ratio test to test for inequality of maternal versus paternal transmission

Gene No. SNP name Paternal TAT Maternal TAT PO-LRTc
T NT P-value ORb T NT P-value ORb ORd P-value
PAX7 1 rs766325 28 16 0.070 1.75 33 20 0.074 1.65 0.90 0.814
2 rs880810 15 17 0.724 0.88 22 19 0.639 1.16 1.28 0.602
3 rs618941 27 29 0.789 0.93 33 15 0.009 2.20 2.31 0.033
4 rs553934 31 30 0.898 1.03 36 15 0.003 2.40 2.38 0.034
5 rs545793 32 26 0.431 1.23 39 29 0.225 1.34 1.10 0.791
6 rs624761 32 23 0.225 1.39 22 29 0.327 0.76 0.56 0.134
7 rs609959 19 10 0.095 1.90 19 18 0.869 1.06 0.56 0.250
PAX3 1 rs3731858 32 21 0.131 1.52 34 27 0.370 1.26 0.82 0.613
2 rs7565552 20 14 0.303 1.43 18 24 0.355 0.75 0.53 0.179
3 rs1370924 27 20 0.307 1.35 29 24 0.492 1.21 0.89 0.782
4 rs1013262 21 18 0.631 1.17 21 27 0.386 0.78 0.67 0.349
5 rs1965791 31 30 0.898 1.03 33 38 0.553 0.87 0.85 0.651
6 rs6717432 35 25 0.197 1.40 34 26 0.302 1.31 0.93 0.843
7 rs1367411 24 19 0.446 1.26 33 30 0.705 1.10 0.88 0.739
8 rs1367414 35 37 0.814 0.95 42 21 0.008 2.00 2.08 0.035
9 rs7609007 31 33 0.803 0.94 30 24 0.414 1.25 1.33 0.441
10 rs1430662 31 30 0.898 1.03 30 24 0.414 1.25 1.21 0.613
11 rs4674639 25 33 0.294 0.76 41 23 0.024 1.78 2.22 0.032
12 rs930140 24 35 0.152 0.69 40 23 0.032 1.74 2.54 0.012
13 rs7600206 17 26 0.170 0.65 33 17 0.024 1.94 2.78 0.018

T, transmitted; NT, not transmitted; OR, odds ratio.

a

TAT analysis was used on trios with matings between two heterozygous parents deleted.

b

OR(transmission): odds ratio of transmission of the high-risk allele.

c

Parent-of-origin likelihood ratio tests (PO-LRT) include separate terms for imprinting.

d

OR: odds ratio for imprinting effect (ie differential transmission from mothers and from fathers).

Shading in the table indicates inferred LD blocks.

Bold values represent results significant at the P<0.05 level.