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. Author manuscript; available in PMC: 2019 Apr 19.
Published in final edited form as: Environ Epidemiol. 2018 Dec;2(4):e028. doi: 10.1097/EE9.0000000000000028

Table 3.

ORs (95% CI) from conditional logistic regression models for ASD per IQRe increase in air-pollutant levels in infancy (9 months after birth) mutually adjusted for pre-pregnancy and pregnancy exposures; stratified models

ORa (95% CI)
NO2e SO2e PM10e PM2.5e
All (N=83,526) 1.08 (1.01, 1.15) 1.21 (1.13, 1.29) 1.04 (1.00, 1.09) 1.06 (1.01, 1.11)

Non-movers
(N=74,834)
1.07 (1.00, 1.15) 1.21 (1.13, 1.29) 1.03 (0.98, 1.08) 1.04 (1.00, 1.10)

Males
(N=64,414)
1.06 (0.99, 1.14) 1.25 (1.16, 1.35) 1.05 (1.00, 1.10) 1.07 (1.01, 1.13)

Females
(N=19,112)
1.12 (0.99, 1.26) 1.11 (0.97, 1.27) 1.01 (0.93, 1.11) 1.02 (0.92, 1.12)

Born   1989–1999
(N=36,190)
1.05 (0.96, 1.14) 1.18 (1.10, 1.27) 1.02 (0.96, 1.08) 1.04 (0.97, 1.11)

Born   2000–2013
(N=47,336)
1.10 (1.01, 1.20) 1.34 (1.15, 1.56) 1.06 (1.00, 1.13) 1.09 (1.02, 1.16)

Copenhagen/large
citiesb
(N=25,908)
1.12 (1.04, 1.22) 1.36 (1.22, 1.50) 1.06 (1.00, 1.13) 1.09 (1.02, 1.17)

Provincial/ruralc
(N=22,772)
1.02 (0.89, 1.15) 1.11 (1.00, 1.23) 1.00 (0.92, 1.08) 1.02 (0.94, 1.11)

Cases from psychiatric
hospitals only
(N=73,174)
1.09 (1.02, 1.16) 1.23 (1.15, 1.32) 1.06 (1.01, 1.11) 1.08 (1.03, 1.14)

Younger cases only d
(N=36,472)
1.13 (1.02, 1.24) 1.44 (1.27, 1.62) 1.08 (1.01, 1.16) 1.14 (1.06, 1.23)
a

adjusted for air pollution levels during pre-pregnancy, pregnancy, and post-pregnancy, as well as all other covariates (maternal age, paternal age, location of birth, neighborhood SES-employment, neighborhood SES-housing, and maternal smoking during pregnancy)

b

Includes Copenhagen and its suburbs, and large cities i.e. Aarhus, Odense and Aalborg

c

Includes larger provincial cities/towns and rural areas and small towns (< 10000 inhabitants)

d

Excludes AD cases with diagnosis age >= 5, Asperger/PDD-NOS cases with diagnosis age >= 10

e

IQRs in controls: NO2: 11.41 ug/m3; SO2: 2.80 ug/m3; PM10: 3.80 ug/m3; PM2.5: 3.61 ug/m3