. Author manuscript; available in PMC: 2019 Dec 1.

Published in final edited form as: Chest. 2018 Jul 17;154(6):1301–1310. doi: 10.1016/j.chest.2018.07.002

Table 3:

Marginal Cox regression models predicting isolated-asthma, isolated-COPD, and asthma/COPD overlap^a^b

Variables	Asthma/COPD Overlap vs. Neither			Isolated-Asthma vs. Neither			Isolated-COPD vs. Neither

	HR	95% CI	p	HR	95% CI	p	HR	95% CI	p
Eosinophils ≥ 300 cells/μl^c	1.85	1.16–2.95	0.009	0.93	0.63–1.36	0.69	1.16	0.82–1.64	0.39
Accelerated FEV₁ decline	2.17	1.40–3.35	<0.001	2.12	1.54–2.91	<0.001	2.18	1.59–2.99	<0.001
Ever smoker	0.92	0.58–1.44	0.70	0.77	0.56–1.05	0.09	1.60	1.18–2.17	0.003
WTC exposure morning of 9/11	1.40	0.84–2.32	0.19	1.58	1.14–2.20	0.006	0.86	0.59–1.26	0.44

Variables	Asthma/COPD Overlap vs. Isolated-Asthma			Asthma/COPD Overlap vs. Isolated-COPD

	HR	95% CI	p	HR	95% CI	p
Eosinophils ≥ 300 cells/μl^c	2.00	1.11–3.62	0.02	1.60	0.89–2.85	0.12
Accelerated FEV₁ decline	1.02	0.60–1.74	0.94	0.99	0.60–1.65	0.98
Ever smoker	1.19	0.69–2.05	0.52	0.57	0.34–0.98	0.04
WTC exposure morning of 9/11	0.88	0.49–1.61	0.68	1.62	0.88–3.01	0.12

N=2,124 due to missing covariates

Adjusted for age, race, BMI, first post-9/11 FEV₁/FVC

First post-9/11 measurement