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. Author manuscript; available in PMC: 2019 Mar 16.
Published in final edited form as: Pain. 2019 Mar;160(3):579–591. doi: 10.1097/j.pain.0000000000001438

Fig. 5. Replicated male-only TMD risk SNP rs13078961 is an eQTL for the 3’UTR of MRAS gene.

Fig. 5.

(a) MRAS has 6 different splice isoforms in the RefSeq database (top), comprising 9 exons (numbered 1–9 inclusively). mRNA levels measured by 9 non-overlapping microarray probes in exons 5–9 were significantly associated with dosage of minor alleles of SNP rs13078961 in human DRGs as discovery (green), blood as replication (blue), and TMD caseness (red). (b) The relative position of microarray probes at 3’ UTR of MRAS (exon 9) associated with SNP rs13078961 in human DRGs (green), blood (blue), and TMD caseness (red). Coordinates are UCSC hg19. For brevity, only the last two digits of probe identifiers are shown; whole probe identifiers are: PSR030135xx.