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. Author manuscript; available in PMC: 2020 Jun 1.
Published in final edited form as: Cell Mol Life Sci. 2019 Feb 7;76(11):2185–2198. doi: 10.1007/s00018-019-03036-1

Figure 3. APA roles in MZT.

Figure 3.

(A) APA origin sub-types and expression abundance (normalized units in average). Maternal (in orange color), maternal-zygotic, zygotic (in green color) and mixed (in grey color) APA sources included 4 (OriA1 – OriA4), 3 (OriB1 – OriB3), 4 (OriC1 – OriC4) and 5 (OriD1 – OriD4) sub-types, respectively. (B) Sharing of APA sites and genes among four APA sources. (C) “Summary” pathway clusgters enriched for each APA origin based on all APA sites. (D) Characterization of DE-APA sites among 16 sub-types of origin (see definitions in (A)). (E) DE-APA sites and DE genes that were shared among four RNA sources of origin. (F) “Summary” pathways enriched for each RNA source of origin based on DE-APA sites only. (G) Examples of genes executing different APA site expression patterns during the MZT period.