Table 1.

Cardiac morphology and systolic function in 3-month-old offspring.

	Con/PBS	Ob/PBS	Ob/ADN	P(ANOVA)
Male offspring	n=7	n=7	n=9
Left ventricle
Anterior wall (diastole) mm	0.52 ± 0.01	0.51 ± 0.01	0.50 ± 0.01	0.34
Anterior wall (systole) mm	0.73 ± 0.01	0.71 ± 0.01	0.71 ± 0.01	0.43
Posterior wall (diastole) mm	0.52 ± 0.01	0.50 ± 0.01	0.50 ± 0.01	0.37
Posterior wall (systole) mm	0.73 ± 0.01	0.71 ± 0.01	0.71 ± 0.01	0.31
Internal volume (diastole) μl	57.3 ± 2.8	66.6 ± 3.1	64.1 ± 3.1	0.12
Internal volume (systole) μl	21.9 ± 2.0	25.6 ± 2.4	23.1 ± 1.9	0.49
Ejection fraction (%)	62.2 ± 1.8	62.0 ± 1.8	64.3 ± 1.8	0.61
Fractional shortening (%)	33.0 ± 1.2	33.0 ± 1.2	34.7 ± 1.4	0.56
Heart rate bpm	502 ± 14	504 ± 12	532 ± 11	0.15
Female offspring	n=10	n=6	n=8
Left ventricle
Anterior wall (diastole) mm	0.51 ± 0.01	0.49 ± 0.01	0.48 ± 0.01	0.26
Anterior wall (systole) mm	0.71 ± 0.02	0.69 ± 0.01	0.69 ± 0.02	0.53
Posterior wall (diastole) mm	0.50 ± 0.01	0.48 ± 0.01	0.48 ± 0.01	0.25
Posterior wall (systole) mm	0.71 ± 0.01	0.69 ± 0.01	0.69 ± 0.02	0.45
Internal volume (diastole) μl	50.3 ± 2.1a	62.6 ± 2.7b	55.6 ± 3.4ab	0.02
Internal volume (systole) μl	18.8 ± 0.9	23.5 ± 2.3	19.7 ± 1.5	0.10
Ejection fraction (%)	62.6 ± 1.1	62.8 ± 2.1	64.6 ± 1.5	0.59
Fractional shortening (%)	33.1 ± 0.8	33.4 ± 1.4	34.6 ± 1.1	0.54
Heart rate bpm	542 ± 13	521 ± 15	529 ± 6	0.44

Mean ± SEM echocardiographic measurements of left ventricular morphology and systolic function, and heart rate in 3 month old offspring of control, PBS infused pregnant mice and obese pregnant mice infused either with PBS or adiponectin from E14.5 to 18.5. Values in bold indicate significant overall effect of maternal treatment group by one-way ANOVA. Values with different superscripts,

^{a or b}, are significantly different from one another by pairwise post-hoc comparison (P<0.05, Holm-Sidak test).