Table 3.

Associations of biomarkers with secondary outcomes

Biomarker	Outcome	β (95% CI)	P-value
Urine Klotho
	Hospital days	−0.18 (−0.36 to −0.0004)	0.05
	MV days	−0.62 (−1.05 to −0.19)	0.005
Urine Klotho/Cr
	Hospital days	−0.27 (−0.47 to −0.08)	0.006
	MV days	−0.98 (−1.57 to −0.38)	0.002
Serum FGF23
	Hospital days	0.23 (0.13 to 0.32)	<0.0001
	MV days	0.45 (0.17 to 0.73)	0.0001
FGF23-to-Klotho/Cr ratio
	Hospital days	0.17 (0.10 to 0.25)	<0.0001
	MV days	0.33 (0.13 to 0.54)	0.002

Hospital survivors only (n=82)

Model 2: Adjusted for age, sex, Charlson Comorbidity Index and non-renal APACHE II score