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. Author manuscript; available in PMC: 2020 Mar 26.
Published in final edited form as: J Neuroimmune Pharmacol. 2019 Aug 10;15(3):538–553. doi: 10.1007/s11481-019-09869-8

Figure 6. Alteration of inhibitory and excitatory synapses and the levels of NLGN2 in the brains of SIV/HIV-infected subjects.

Figure 6.

(a, d) Representative confocal images of the frontal cortex regions of SIV/HIV-infected subjects were stained with Gephyrin (inhibitory postsynaptic marker) and PSD95 (excitatory postsynaptic marker). (b, e) Quantification of Gephyrin and PSD95 puncta. (c, d and g, h) Expression level of NLGN2 is significantly reduced in the brains of SIV/HIV-infected subjects. Bars represent mean ± SD from 3 independent experiments. * p < 0.05; ** p < 0.01 vs. uninfected controls.