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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: AJNR Am J Neuroradiol. 2019 Oct 24;40(11):1855–1863. doi: 10.3174/ajnr.A6251

Table 4.

Per patient and per lesion sensitivity and specificity using generalized estimating equations (GEE) for target neurologic findings account for acute neurologic deficit.

Dose-Kernel Configuration Per-patient Sensitivity for CT Findings Accounting for Acute Neurologic Deficit
GEE % (95% C.I.) (range%)
Per-patient Specificity for CT Findings Accounting for Acute Neurologic Deficit
GEE % (95% C.I.) (range%)
Target Lesion Sensitivity for CT Findings Accounting for Acute Neurologic Deficit
GEE% (95% C.I.) (range%)
250 eff. mAs IR 81.7 (71.1 to 92.3) (78.6, 83.3) 93.5 (88.9 to 98.1) (85.4, 100.0) 71.0 (64.8 to 77.1) (65.7, 74.3)
200 eff. mAs FBP 79.4 (68.2 to 90.6) (76.2, 83.3) 91.9 (87.5 to 96.3) (80.5, 100.0) 68.6 (62.3 to 74.9) (61.4, 72.9)
100 eff. mAs IR 77.0 (65.5 to 88.5) (73.8, 81.0) 88.6 (82.8 to 94.4) (73.2, 95.1) 68.1 (61.8 to 74.4) (64.3, 71.4)
100 eff. mAs FBP 74.6 (62.4 to 86.8) (69.0, 78.6) 87.0 (81.1 to 92.9) (75.6, 95.1) 62.9 (56.3 to 69.4) (57.1, 65.7)
50 eff. mAs IR 73.8 (62.3 to 85.4) (66.7, 78.6) 88.6 (82.8 to 94.4) (75.6, 97.6) 60.5 (53.9 to 67.1) (52.9, 65.7)
50 eff. mAs FBP 72.2 (60.6 to 83.8) (71.4, 73.8) 83.7 (77.7 to 89.8) (69.8, 86.0) 61.0 (54.4 to 67.6) (60.0, 62.9)
25 eff. mAs IR 65.9 (53.3 to 78.4) (61.9, 71.4) 88.6 (82.4 to 94.8) (85.4, 92.7) 53.3 (46.6 to 60.1) (45.7, 62.9) [a]
[a]

95% confidence interval does not overlap with routine dose, so dose-reconstruction configuration is significantly worse.