Fig 5 –

(a & b) A 4-year-old female with molecular diagnosis of high grade glioma (GBM_MYCN). Axial DWI (a) and sagittal post contrast T1 weighted (b) images demonstrate a large mass centered in the left frontal lobe with prominent necrotic/cystic areas centrally; diffusion restriction and moderate heterogenous enhancement of the solid component. (c & d) A 4-year-old male with molecular diagnosis of ependymoma (EPN_RELA). Axial DWI (c) and sagittal post contrast T1 weighted (d) images demonstrate a large mass centered deep in the left hemisphere with prominent necrotic/cystic areas centrally; diffusion restriction and moderate heterogenous enhancement of the solid component. Note the similarities in age and imaging appearance between these two cases with different molecular diagnoses.