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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: AJNR Am J Neuroradiol. 2019 Nov 6;40(11):1871–1877. doi: 10.3174/ajnr.A6283

Figure 2.

Figure 2.

Representative axial T2-FLAIR image and maps of macromolecular tissue volume (MTV) reflecting myelin content, axonal volume fraction (AVF), and g-ratio in a patient with RRMS. The top row shows a lesion with an elevated g-ratio (0.95), indicating a greater degree of demyelination relative to axonal loss. The bottom row shows a lesion with concordant axonal and myelin loss, which is reflected by a g-ratio similar to that of NAWM (0.69). For comparison, the conventional T2-FLAIR images do not demonstrate a significant difference in contrast between the two lesions.