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. Author manuscript; available in PMC: 2010 Mar 23.
Published in final edited form as: J Neurosci. 2009 Sep 23;29(38):11954–11964. doi: 10.1523/JNEUROSCI.2643-09.2009

Figure 8.

Figure 8

Mean body temperature (Tb) of the combined preoptic (MnPO+DLPO) lesion group (A), MnPO lesion group (B), and DLPO lesion group (C) over 3 consecutive days. Higher Tb was observed throughout the entire day (dark and light periods) in the combined (MnPO+DLPO) lesion group (A) but not in the MnPO lesion (B) or DLPO lesion (C) groups. Graphs D, E, and F show the fever response after LPS injection in control animals compared to the combined (MnPO+DLPO) lesion group (D), MnPO lesion group (E), and DLPO lesion group (F). LPS was injected at time 0. The DLPO lesion group showed a similar pattern of temperature increase as control animals (F), but neither the combined (MnPO+DLPO) or MnPO lesion groups showed this raise in temperature (D and E, respectively). Significant differences between groups are noted by asterisks (p<0.05; repeated measures ANOVA followed by paired t-tests for comparisons at each time point). All values are the mean ± S.E.M.