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. Author manuscript; available in PMC: 2020 Mar 16.
Published in final edited form as: Pigment Cell Melanoma Res. 2020 Jan 22;33(2):264–278. doi: 10.1111/pcmr.12853

TABLE 1.

Syngeneic mouse cutaneous melanoma models for simulating uveal melanoma

Cell line Source Original publication (Laboratory of origin) Inoculation method Metastasis References
B16LS9 Mouse cutaneous melanoma Rusciano et al. (1994) (Max Burger) Suprachoroidal Liver, lungs, and lymph nodes Jones et al. (2019); Dong et al. (2019); Xue et al. (2015); Yang et al. (2016), Yang and Grossniklaus (2010), Yang, Jager, and Grossniklaus (2010), Yang, Xu, luvone, and Grossniklaus (2006); Lattier et al. (2013); Zhang et al. (2011); Alizadeh et al. (2003); Dithmar, Rusciano, and Grossniklaus (2000), Dithmar, Rusciano, Lynn, et al. (2000); Diaz, Rusciano, Dithmar, and Grossniklaus (1999)
Ant. chamber Not reported Han, Brown, and Niederkorn (2016)
Intravitreal Liver Han et al. (2016); Yang et al. (2011)
Intrasplenic
Intrahepatic Not reported Xue et al. (2015)
B16F10 Mouse cutaneous melanoma Fidler, Gersten, and Budmen (1976) (Marilyn Budmen) Suprachoroidal None Grossniklaus, Barron, and Wilson (1995)
Ant. chamber Not reported el Filali et al. (2012); de Lange et al. (2012); Ly et al. (2010); Grossniklaus et al. (1995); Knisely and Niederkorn (1990);
Lungs Harning and Szalay (1987); Niederkorn, Sanborn, and Gamel (1987), Niederkorn (1984)
Tail vein Lungs Sanborn, Niederkorn, and Gamel (1992); Niederkorn et al. (1987)
Queens Mouse cutaneous melanoma Harning et al. (1987) (Jeanne Szalay) Suprachoroidal Lungs Rajaii et al. (2014); Grossniklaus et al. (1995)
Ant. chamber None Grossniklaus et al. (1995)
Lungs Sanborn, Niederkorn, Kan-Mitchell, and Albert (1992), Sanborn, Niederkorn, and Gamel (1992); Harning and Szalay (1987)
Tail vein Lungs Sanborn, Niederkorn, and Gamel (1992)
HCmel12 Mouse cutaneous melanoma Kilian et al. (2016) (Thomas Tüting) Intravitreal Lungs and lymph nodes Stei, Loeffler, Kurts, et al. (2016); Kilian et al. (2016)
Oncogene-transduced melan-A cells Immortalized mouse melanocyte Bennett, Cooper, and Hart (1987) (Ian Hart) Subcutaneous Not reported Moore et al. (2016)
Lungs and liver Van Raamsdonk et al. (2010)

Abbreviation: Ant. chamber, anterior chamber.