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. Author manuscript; available in PMC: 2021 May 31.
Published in final edited form as: Mol Psychiatry. 2020 May 6;26(5):1634–1646. doi: 10.1038/s41380-020-0756-y

Table 2b.

Quality control parameters for magnetic resonance spectra determined from LCModel.

CRAMER RAO LOWER BOUND (CRLB)

Thalami ASD TD P
Cho 3.95 ± 1.28 4.25 ± 2.02 0.588
Glx 21.24 ± 10.55 21.01 ± 18.83 0.798
mI 23.71 ± 11.65 18.78 ± 8.52 0.081
NAA 6.86 ± 3.90 6.75 ± 3.53 0.932
Cr+PCr 4.24 ± 1.09 4.94 ± 3.77 0.423
Left DLPFC
Cho 5.29 ± 2.39 5.93 ± 3.39 0.606
Glx 15.82 ± 12.10 19.95 ± 20.76 0.241
mI 14.41 ± 7.23 15.29 ± 7.35 0.935
NAA 8.41 ± 4.62 7.27 ± 3.69 0.272
Cr+PCr 4.12 ± 1.90 5.00 ± 2.90 0.341

SIGNAL-TO-NOISE RATIO (SNR) and FULL WIDTH AT HALF MAXIMUM (FWHM)

Thalami ASD TD P
SNR 16.59 ± 6.65 15.59 ± 6.11 0.559
FWHM 0.071 ± 0.018 0.077 ± 0.026 0.270
Left DLPFC
SNR 15.56 ± 6.35 17.75 ± 8.09 0.299
FWHM 0.096 ± 0.029 0.114 ± 0.043 0.105

Note: Values reported are mean ± SD. P-values are from Welch two-sample T-test performed between ASD and TD groups. Abbreviations: Cho = choline; Glx = sum of glutamine and glutamate; mI = myo-inositol; NAA = N-acetylaspartate; Cr+PCr = creatine + phosphocreatine.