Table 2. Evaluation of data imputation methods.

Mean results of 100 random experiments with standard deviations given in parentheses, in units of the last significant digit of the mean. MAD: Median Absolute Deviation, MAE: Mean Absolute Error, RMSE: Root-Mean-Square Error.

Error	Method	Clashscore	RSRZ outliers [%]	Ramachandran outliers [%]	Rotamer outliers [%]	R free [%]
MAD	MICE	2.5(3)	2.01(2)	0.21(1)	1.23(3)	1.02(2)
	Mean	4.4(3)	2.30(2)	0.49(1)	2.11(4)	2.50(4)
	Median	2.9(3)	1.86(2)	0.04(1)	1.39(4)	2.50(4)
MAE	MICE	3.7(4)	2.54(3)	0.41(2)	1.77(4)	1.31(2)
	Mean	5.7(6)	2.74(3)	0.61(2)	2.56(6)	3.00(3)
	Median	5.1(7)	2.60(3)	0.49(3)	2.34(7)	3.00(3)
RMSE	MICE	5.7(15)	3.84(15)	0.84(11)	2.64(10)	1.77(3)
	Mean	8.9(23)	4.04(14)	1.24(16)	3.65(14)	3.82(4)
	Median	9.3(24)	4.17(14)	1.32(16)	3.85(15)	3.82(4)