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. Author manuscript; available in PMC: 2010 Apr 28.
Published in final edited form as: J Neurosci. 2009 Oct 28;29(43):13435–13444. doi: 10.1523/JNEUROSCI.3257-09.2009

Figure 2.

Figure 2

Macrophages with an M1 phenotype dominate sites of spinal cord injury. (A) CD16/32+ M1 macrophages and arginase I+ M2 macrophages coexist at the lesion epicenter during the first week post-injury; however, only M1 macrophages persist until 28 dpi. (B) Quantitation of macrophages expressing M1 and M2 phenotypic markers as a function of time post-SCI. (C) When expressed as a ratio of M1:M2 cells, there is an obvious shift towards a M1 macrophage phenotype after the first week post-injury. (M1 and M2 markers; red, AF546 and nuclear stain with DAPI; blue); scale bar = 20μm.