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. Author manuscript; available in PMC: 2010 Apr 28.
Published in final edited form as: J Neurosci. 2009 Oct 28;29(43):13435–13444. doi: 10.1523/JNEUROSCI.3257-09.2009

Figure 7.

Figure 7

M2 macrophages enhance axon growth on an inhibitory myelin (MAG) substrate. DRG neurons plated on a monolayer of CHO cells engineered to express MAG (Domeniconi et al., 2002) were treated with M1 or M2 MCM for 48 hrs then neurite outgrowth was assessed. M2 MCM increased the number (A) and length (B) of neurites extending from DRG neurons (A; p<0.05). Representative β-tubulin III+ DRG neurons are provided showing the median number and length of neurites elicited by M1 or M2 MCM (C). These data represent mean of n= 20–25 neurons analyzed from an individual experiment.