KEY RESOURCES TABLE
| REAGENT or RESOURCE | SOURCE | IDENTIFIER |
|---|---|---|
| Antibodies | ||
| Anti-CD63 Antibody | BD PharMingen | Cat# 556019; RRID:AB_396297 |
| Anti-AGO2 Antibody | Abcam | Cat# ab57113; RRID:AB_2230916 |
| Anti-PLAP Antibody | Abcam | Cat# ab118856; RRID:AB_10900125 |
| Biological Samples | ||
| Maternal Serum | UCSD Placental Dysfunction Clinic | |
| Maternal Serum | Sera Prognostics Repository | |
| Critical Commercial Assays | ||
| miRNeasy micro kit | QIAGEN | 217084 |
| mirVana miRNA Isolation Kit, without phenol | ThermoFisher Scientific | AM1561 |
| RNA Clean & Concentrator-5 | Zymo Research | R1013 |
| DNA Clean & Concentrator-5 | Zymo Research | D4013 |
| Quant-iT RiboGreen RNA Assay Kit | ThermoFisher Scientific | R11490 |
| Quant-iT PicoGreen dsDNA Assay Kit | ThermoFisher Scientific | P11496 |
| Agilent RNA 6000 Pico Kit | Agilent Technologies | 5067–1513 |
| Agilent RNA 6000 Nano Kit | Agilent Technologies | 5067–1511 |
| Bioanalyzer High Sensitivity DNA Analysis | Agilent Technologies | 5067–4626 |
| NEBNext Small RNA Library Prep Set for Illumina (Multiplex Compatible) | New England Biolabs | E7330L |
| Deposited Data | ||
| Small RNA-seq data, miRNA | This paper | See https://www.ncbi.nlm.nih.gov/gap/, phs002016.v1.p1 |
| Software and Algorithms | ||
| exceRpt small RNA-seq pipeline for exRNA profiling | Genboree Bioinformatics | http://www.genboree.org/site/ |