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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Cancer Immunol Immunother. 2020 May 24;69(10):2113–2124. doi: 10.1007/s00262-020-02607-7

Figure 7. B1 cell-intrinsic TLR4 and TRIF expression is required for B1 cell-elicited protection against peritoneal carcinomatosis.

Figure 7.

(A–D) CD19−/− mice were challenged with 2×104 TA3-Ha cells i.p.± MPL/TDCM treatment on d0 and monitored for survival (p<0.05 shown for Log rank test; n=6–11 mice per group). In B–D, CD19−/− mice were reconstituted with 2×106 purified peritoneal B1 cells i.p. one day before challenge. Results representative of 2 independent experiments. In B, the p value indicates Log-rank results.