Table 6:

Odds Ratios of Total Knee Replacement for Clinical Risk Factors and Radiographic Readings

Parameter	Crude Odds Ratio	Adjusted Odds Ratio	P Value*
DL-TL†	55 (26, 119)	6.0 (2.1, 17)	<.001
DL-TL-MT	82 (34, 194)	7.7 (2.3, 25)	<.001
Kellgren-Lawrence	4.0 (3.0, 5.3)	1.9 (1.2, 3.1)	.009
Body mass index	1.7 (1.4, 2.2)	1.4 (1.0, 1.9)	.04
OARSI	19 (10, 36)	1.2 (0.4, 3.5)	.73
KOOS QoL	0.96 (0.95, 0.97)	0.98 (0.96, 0.997)	.02
WOMAC	1.31 (1.23, 1.39)	1.06 (0.96, 1.18)	.26
Contralateral knee
Kellgren-Lawrence	1.8 (1.5, 2.1)	1.1 (0.7, 1.7)	.79
OARSI	3.6 (2.6, 5.1)	1.1 (0.4, 3.2)	.80
WOMAC	1.12 (1.06, 1.18)	1.01 (0.92, 1.11)	.87

Note.—Data in parenthesis are 95% confidence intervals. Multivariable analysis was performed by using risk factors from 364 patients and 364 control patients. P values are for adjusted odds ratios. All P values for the crude odds ratios are <.001 for the risk factors in the table. DL = deep learning, KOOS QoL = Knee-related Quality of Life from Knee injury and Osteoarthritis Outcome Score, MT = multitask, OARSI = Osteoarthritis Research Society International, TL = transfer learning, WOMAC = Western Ontario and McMaster Universities Osteoarthritis Index.

^*Wald test was used to assess the significance levels of individual risk factors.

^†DL-TL model is used to demonstrate the effect of addition of Kellgren-Lawrence-grade task into the total knee replacement prediction model only. Adjusted odds ratios presented after the first row are calculated from a multivariable analysis of risk factors and DL-TL-MT model.