Stereoview of the K330L HDAC6 CD1–SAHA-BPyne complex (PDB 6WYP). Polder omit maps showing SAHA-BPyne bound to monomer A and L330 (each contoured at 2.5 σ). Atoms are color-coded as follows: C = light blue (monomer A), light gray (symmetry mate), or wheat (inhibitor), N = blue, O = red, Zn2+ = gray sphere, and solvent = small red spheres. Metal coordination and hydrogen bond interactions are indicated by solid and dashed black lines, respectively.