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. Author manuscript; available in PMC: 2020 Sep 25.
Published in final edited form as: Mol Reprod Dev. 2020 Jun 17;87(7):763–772. doi: 10.1002/mrd.23392

Table 2.

Normalized abundance ± SEM of gene products related to glycolysis and mitophagy. Treatments include a control (cultured at 5% O2 for 3 days), CoCl2 treatment (100 μM CoCl2 for 24 hours), and a hypoxic treatment (cultured at 1% O2 for 3 days). Superscripts represent differences between treatments with P < 0.05 considered significant.

Gene name Control CoCl2 Hypoxia
SLC2A1 1.88 ± 0.38a 3.25 ± 0.32b 2.29 ± 0.12ab
SLC2A3 1.61 ± 0.26a 3.25 ± 0.39b 3.75 ± 0.34b
HK1 2.02 ± 0.17 a 3.30 ± 0.25 b 3.02 ± 0.18 b
HK2 10.59 ± 1.92a 22.36 ± 1.68b 19.24 ± 1.03b
GAPDH 3.27 ± 0.34a 6.38 ± 0.49b 4.33 ± 0.44b
PGK1 1.03 ± 0.10a 2.06 ± 0.09b 1.77 ± 0.10b
ENO1 5.88 ± 0.44a 10.28 ± 0.68b 9.15 ± 0.97b
PKM2 3.70 ± 0.25a 6.30 ± 0.59b 5.59 ± 0.48b
PDK1 3.82 ± 0.48a 7.10 ± 0.05b 5.66 ± 0.51c
LDHA 2.16 ± 0.22a 3.45 ± 0.28b 3.57 ± 0.26b
LDHB 0.11 ± 0.01 0.11 ± 0.001 0.12 ± 0.02
BNIP3 2.02 ± 0.40a 5.54 ± 0.32b 3.69 ± 0.31c
TALDO1 0.81 ± 0.10 1.03 ± 0.09 0.85 ± 0.09
EPAS1 0.32 ± 0.07 0.55 ± 0.17 0.24 ± 0.04
YWHAG 0.39 ± 0.04 0.44 ± 0.04 0.39 ± 0.02
BCL2 0.55 ± 0.03 0.65 ± 0.07 0.53 ± 0.05

indicates genes that are HIF targets.