Table 3.
Normalized abundance ± SEM of gene products related to glycolysis and mitophagy. Treatments include day 6 blastocyst stage embryos created from control donor cells and CoCl2 treated donor cells (100 μM CoCl2 for 24 hours). Superscripts represent differences between treatments with P < 0.05 considered significant.
| Gene name | Control | CoCl2 | p-value |
|---|---|---|---|
| SLC2A1 | 5.86 ± 0.66a | 8.06 ± 0.44b | 0.0497 |
| SLC2A3 | 2.05 ± 0.47 | 2.74 ± 0.16 | 0.2370 |
| HK1 | 0.12 ± 0.01 | 0.16 ± 0.03 | 0.0978 |
| HK2 | 24.30 ± 3.32 | 30.87 ± 2.68 | 0.0989 |
| GPI | 0.66 ± 0.10 | 0.88 ± 0.04 | 0.0917 |
| ALDOC | 0.37 ± 0.12 | 0.50 ± 0.03 | 0.3755 |
| GAPDH | 2.45 ± 0.52 | 2.38 ± 0.50 | 0.4626 |
| PGK1 | 0.18 ± 0.02 | 0.25 ± 0.04 | 0.0955 |
| PGAM1 | 3.08 ± 0.10a | 3.88 ± 0.26b | 0.0446 |
| ENO1 | 1.31 ± 0.12 | 1.55 ± 0.09 | 0.0916 |
| PKM2 | 0.47 ± 0.11 | 0.66 ± 0.11 | 0.1518 |
| PDK1 | 2.26 ± 0.58 | 2.48 ± 0.56 | 0.3997 |
| LDHA | 0.08 ± 0.01a | 0.15 ± 0.02b | 0.0315 |
| BNIP3 | 4.99 ± 0.66 | 6.76 ± 0.68 | 0.1348 |
| TALDO1 | 3.90 ± 0.45 | 4.58 ± 0.74 | 0.2414 |
| YWHAG | 0.09 ± 0.01 | 0.13 ± 0.03 | 0.1302 |
| BCL2 | 4.49 ± 0.57 | 4.94 ± 0.69 | 0.6432 |
| POU5F1 | 476.97 ± 136.52 | 614.25 ± 35.49 | 0.1928 |
| VEGFA | 2.99 ± 0.23 | 3.73 ± 0.53 | 0.2678 |