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. Author manuscript; available in PMC: 2020 Sep 24.
Published in final edited form as: Circ Res. 2020 Jul 30;127(8):997–1022. doi: 10.1161/CIRCRESAHA.120.317295

Figure 2. Protein-interaction network analysis reveals numerous interactions of proteins that are differentially abundant in aortas of SR-uPA+/0 mice.

Figure 2.

A protein-protein relational network was built based on experimentally validated direct interactions. The network is comprised of 87 proteins, each portrayed as a circular node (all nodes are identified in Online Data Set V). Key highly connected nodes (hubs) are labeled together with 2 members of the matrix metalloproteinase family of extracellular proteases, and several extracellular matrix components.