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. Author manuscript; available in PMC: 2020 Dec 31.
Published in final edited form as: Blood Cancer Discov. 2020 Sep 15;1(3):258–273. doi: 10.1158/2643-3230.BCD-20-0132

Figure 5: Summary of structural variant hotspots.

Figure 5:

Summary of all 68 SV hotspots, showing (from the top): absolute and relative contribution of SV classes within 100 Kb of the hotspot; involvement of active enhancers in multiple myeloma, presence of putative driver gene fusions and copy number changes; differential expression of putative driver genes by copy number changes and/or SV involvement by linear regression; total number of genes in each hotspot differentially expressed by SV involvement (FDR < 0.1) after adjustment for copy number changes; known and candidate driver genes.