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. Author manuscript; available in PMC: 2020 Aug 28.
Published in final edited form as: Semin Arthritis Rheum. 2020 Aug 28;50(5):822–826. doi: 10.1016/j.semarthrit.2020.08.002

Table 1:

Unit Cost paid by Medicare of conventional DMARD used for RA between 2012–17

Drug Name 2012 (Actual Cost) 2017 (Actual Cost) 2017 (2012 cost in 2017 dollars) Percentage Increase in Adjusted costs from 2012 to 2017

Leflunomide
- Generic $1.68 $4.31 $1.92 124%
- Branded $22.49 $38.49 $25.65 50%

Methotrexate
- Generic (oral) $0.64 $1.89 $0.73 159%
- Branded (oral)* $9.60 $10.01 $10.95 −9%
- Branded (injectable)** $334.90 $375.90 $381.91 −2%

Hydroxychloroquine
- Generic $0.29 $1.84 $0.33 458%
- Branded $4.18 $8.40 $4.77 76%

Sulfasalazine $0.16 $0.19 $0.18 6%
*

indicates drugs that ceased to be covered in 2016

**

indicates drugs that were approved in 2014