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. Author manuscript; available in PMC: 2020 Oct 17.
Published in final edited form as: AJNR Am J Neuroradiol. 2018 Jan 18;39(3):427–434. doi: 10.3174/ajnr.A5507

Table 3:

DTI derivate metrics in patients with MNGIE and healthy controls

ROI MD (Mean ± SD) FA (Mean ± SD) AD (Mean ± SD) RD (Mean ± SD)
PO-WM
 MNGIE 1.09 ± 0.16 0.27 ± 0.05 1.40 ± 0.16 0.93 ± 0.16
 Controls 0.79 ± 0.05 0.40 ± 0.02 1.14 ± 0.07 0.61 ± 0.05
P Valuea <.0001b <.0001b .0001b <.0001b
OR
 MNGIE 1.15 ± 0.20 0.41 ± 0.07 1.69 ± 0.19 0.88 ± 0.21
 Controls 0.81 ± 0.05 0.59 ± 0.09 1.35 ± 0.12 0.54 ± 0.06
P Valuea <.0001b .0003b .0002b <.0001b
PLIC
 MNGIE 0.78 ± 0.06 0.61 ± 0.07 1.40 ± 0.06 0.47 ± 0.08
 Controls 0.69 ± 0.05 0.70 ± 0.04 1.36 ± 0.11 0.35 ± 0.05
P Valuea .0019b .0008b 0.36 .0003b
CC
 MNGIE 0.88 ± 0.08 0.66 ± 0.06 1.64 ± 0.11 0.49 ± 0.10
 Controls 0.81 ± 0.09 0.76 ± 0.06 1.72 ± 0.19 .35 ± 0.08
P Valuea .12 .0012b 0.37 .0028b

Note:—OR indicates optic radiation; CC, corpus callosum.

a

Statistical significance was set at P < .003 after Bonferroni correction for multiple comparisons.

b

Significant.