Table 2.

Association between self-reported recency of marijuana use and biomarkers of inflammation in Wave 1 of PATH

	β (95% Confidence interval)
	Crude	Model 1	Model 2	Model 3
Recency of marijuana use	High sensitivity C reactive protein (mg/L)
Never	Reference	Reference	Reference	Reference
More than a year ago	0.01 (−0.15, 0.17)	0.09 (−0.08, 0.26)	0.01 (−0.17, 0.19)	0.00 (−0.16, 0.17)
Within the past year	−0.06 (−0.31, 0.19)	0.08 (−0.14, 0.31)	0.00 (−0.21, 0.22)	0.06 (−0.16, 0.30)
Within the past 30 days	−0.26 (−0.43, −0.10)	−0.09 (−0.26, 0.06)	−0.20 (−0.38, −0.02)	−0.15 (−0.32, 0.00)
Recency of marijuana use X Sex
P-value for interaction				0.1263
	Interleukin-6 (pg/ml)
Never	Reference	Reference	Reference	Reference
More than a year ago	−0.00 (−0.08, 0.08)	0.06 (−0.01, 0.14)	−0.00 (−0.07, 0.07)	−0.00 (−0.07, 0.06)
Within the past year	−0.04 (−0.19, 0.10)	0.14 (0.00, 0.27)	0.09 (−0.04, 0.24)	0.13 (−0.00, 0.27)
Within the past 30 days	−0.13 (−0.21, −0.05)	0.05 (−0.02, 0.13)	−0.04 (−0.12, 0.04)	−0.02 (−0.10, 0.05)
Recency of marijuana use X Sex
P-value for interaction				0.8134
	Fibrinogen (mg/dL)
Never	Reference	Reference	Reference	Reference
More than a year ago	−0.02 (−0.05, 0.00)	0.00 (−0.02, 0.02)	−0.01 (−0.03, 0.01)	−0.01 (−0.03, 0.01)
Within the past year	−0.03 (−0.13, 0.05)	0.02 (−0.06, 0.10)	0.01 (−0.06, 0.09)	0.02 (−0.05, 0.10)
Within the past 30 days	−0.06 (−0.10, −0.03)	−0.00 (−0.03, 0.03)	−0.01 (−0.05, 0.01)	−0.01 (−0.04, 0.02)
Recency of marijuana use X Sex
P-value for interaction				0.5411

Note:

Mode 1 was adjusted for age and sex

Model 2 was adjusted for age, sex, race/ethnicity status, educational attainment, anti-inflammatory medication use, alcohol use, recency of smoking and any illicit drug use in past 12 months

Model 3 was additionally adjusted for BMI