Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Effect of CIC variants on binding of folic acid and cellular folate concentration. (A) Folic acid surface binding by HeLa cells stably expressing GFP, GFP-CIC WT or GFP-CIC p.R353X. Cells were exposed to 5 nmol/L [3H] folic acid binding was calculated relative to GFP transfected cells (n≥3, each carried out in duplicate), **p<0.01. (B) Folate concentration in control iPSCs and family 1 proband iPSCs, *p<0.05.
