Table 2.

Topoisomerase IIα inhibition. Values shown correspond to the IC₅₀ ± SD.

Compound 1	Compound 2	Compound 3	Compound 4	Compound 5	Compound 6	Compound 7
160 ± 20 µM	not active	160 ± 20 µM	160 ± 20 µM	200 ± 15 µM	not active	not active
Compound 8	Compound 9	Compound 10	Compound 11	Compound 12	Compound 13	Compound 14
not active	not active	220 ± 30 µM	170 ± 15 µM	not active	not active	2 ± 0.5 µM