Table 3.
Cell proliferation results in various cancer cell lines (A549: lung adenocarcinoma, DU145: androgen-independent prostate cancer, MCF7: breast adenocarcinoma, HeLa: cervical carcinoma, A375: Human melanoma and G-361: Human melanoma. Values shown correspond to the IC50 (µM) ± SD of at least two independent experiments.
| Cell line | 1 | 3 | 4 | 10 | 11 | 14 | Etoposide |
|---|---|---|---|---|---|---|---|
| DU145 | 15.1 ± 5.5 | 17.9 ± 7.4 | 11.1 ± 6.5 | 10.5 ± 6.0 | 8.8 ± 1.5 | 11.5 ± 1.3 | 0.5 ± 0.2 |
| A549 | 19.4 ± 1.8 | 23.3 ± 2.3 | 17.8 ± 0.6 | 22.9 ± 6.5 | 18.0 ± 0.1 | 17.1 ± 8.7 | 2.4 ± 2.0 |
| HeLa | 17.0 ± 1.9 | 17.1 ± 3.2 | 21.8 ± 4.6 | 20.8 ± 4.5 | 17.2 ± 2.6 | 38.2 ± 9.1 | 1.2 ± 0.4 |
| MCF7 | 13.9 ± 2.3 | 14.2 ± 2.5 | 16.2 ± 2.6 | 16.0 ± 0.5 | 15.8 ± 1.4 | 15.8 ± 1.3 | 8.9 ± 1.6 |
| A375 | 9.9 ± 0.1 | 10.7 ± 0.1 | 10.8 ± 0.1 | 12.3 ± 1.8 | 15.1 ± 4.8 | 12.6 ± 0.7 | 0.5 ± 0.1 |
| G361 | 1.4 ± 0.4 | 1.6 ± 0.5 | 1.8 ± 0.6 | 3.0 ± 0.7 | 6.6 ± 3.1 | 8.1 ± 2.9 | 3.8 ± 3.0 |