Skip to main content
. Author manuscript; available in PMC: 2021 Mar 25.
Published in final edited form as: FASEB J. 2021 Mar;35(3):e21298. doi: 10.1096/fj.202001706RR

Figure 1. High fat feeding leads to whole body diurnal metabolic inflexibility.

Figure 1.

(A) Body weight was assessed once every 2-wks, in mice that were fed either a control or high fat diet in an ad libitum fashion for 20-wks (n=20–21). (B) After 20-wks of control or high fat diet feeding, body weight (i), fat mass (ii) and lean mass (iii) were assessed (n=5). (C) After 18-wks of control or high fat diet feeding, 24-hr patterns in caloric intake (i), physical activity (ii), energy expenditure (iii), and respiratory exchange ratio (RER; iv) were assessed (n=25–27). Data are reported as mean ± SEM. Main effects for either time, diet, and/or interaction are reported at the top of the figure panels. *p<0.05 for control (circle) vs high fat (square).