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. Author manuscript; available in PMC: 2021 Mar 3.
Published in final edited form as: Curr Protoc. 2021 Feb;1(2):e32. doi: 10.1002/cpz1.32

Figure 6.

Figure 6.

SASP proteomic analysis figures generated by the Spectronaut software. A) Heatmap depicting the abundance of all proteins identified in the conditioned medium of oncogenic Ras-induced senescent (n=6) and control (n=6) IMR-90 cells. B) Volcano plot of the log2 fold changes in abundance of proteins secreted by senescent versus control cells. Red dots represent fold changes greater than 1.5-fold, and p-values less than 0.05. C) Line plot showing the abundance of a classical SASP protein, MMP1, in the secretomes of senescent and non-senescent cells.