Table 2:
Characteristics of intubated COVID-19 patients by survival status.
| Total | Survived | Died | P | |
|---|---|---|---|---|
| Number | 243 | 155 (63.8) | 88 (36.2) | |
| Age (y) | 62.8 (14.9) | 58.1 (14.0) | 71.0 (12.7) | <0.001 |
| Female sex (%) | 39.1 | 36.8 | 43.2 | 0.33 |
| Hispanic ethnicity (%) | 22.2 | 27.1 | 13.6 | 0.017 |
| African-American race (%) | 35.4 | 36.1 | 34.1 | 0.75 |
| Chronic lung disease (%) | 22.2 | 18.7 | 28.4 | 0.082 |
| Congestive heart failure (%) | 28.8 | 25.1 | 35.2 | 0.097 |
| Hypertension (%) | 60.9 | 56.8 | 68.2 | 0.081 |
| Chronic immunodeficiency (%) | 23.9 | 19.4 | 31.8 | 0.03 |
| Diabetes with complication (%) | 19.3 | 18.7 | 20.5 | 0.74 |
| Chronic kidney disease (%) | 20.1 | 11.6 | 35.2 | <0.0001 |
| Temperature (C) | 38.2 (1.1) | 38.4 (1.0) | 38.0 (1.2) | 0.017 |
| Heart rate (beats per minute) | 113 (21) | 112 (20) | 116 (23) | 0.17 |
| Systolic BP (mmHg) | 84 (15) | 86 (14) | 81 (17) | 0.016 |
| Diastolic BP (mmHg) | 47 (9) | 48 (9) | 46 (8) | 0.066 |
| Respiratory rate (breaths per minute) | 35 (7) | 34 (7) | 36 (7) | 0.15 |
| Vasopressor use (%) | 87.2 | 90.3 | 81.8 | 0.06 |
| Weight (kg) | 87.5 (27.2) | 89.7 (25.0) | 83.6 (30.5) | 0.11 |
| Body-mass index (kg/m2) | 30.9 (8.3) | 31.5 (7.9) | 29.7 (8.9) | 0.13 |
| Tidal volume (mL) | 414 (66) | 409 (61) | 422 (72) | 0.18 |
| Positive end-expiratory pressure (cm H2O) | 12.4 (4.3) | 12.7 (4.2) | 11.8 (4.4) | 0.13 |
| Driving pressure (cmH2O) | 15.9 (18.2) | 14.5 (11.1) | 18.3 (26.4) | 0.18 |
| Lung compliance (mL/cm H2O) | 30.6 (15.4) | 29.1 (12.7) | 33.2 (18.9) | 0.11 |
| Minute ventilation (L/min) | 14.7 (23.2) | 12.7 (11.8) | 18.3 (35.1) | 0.1 |
| pH | 7.3 (0.1) | 7.31 (0.1) | 7.29 (0.1) | 0.38 |
| pCO2 (mmHg) | 49.5 (14.2) | 51.4 (13.2) | 46.3 (15.4) | 0.032 |
| pO2 (mmHg) | 73 (36) | 70 (28) | 78 (47) | 0.19 |
| PaO2/FIO2 ratio | 99 (75) | 97 (65) | 101 (90) | 0.78 |
| Creatinine (mg/dL) | 2.2 (2.8) | 1.8 (2.4) | 2.9 (3.4) | 0.004 |
| Bilirubin (mg/dL) | 0.7 (0.5) | 0.7 (0.5) | 0.8 (0.6) | 0.26 |
| Lactate (mmol/L) | 2.6 (3.4) | 2.0 (2.4) | 3.6 (4.6) | 0.005 |
| Hemoglobin (g/dL) | 11.2 (2.2) | 11.2 (2.3) | 11.1 (2.1) | 0.78 |
| Hematocrit (%) | 35 (7) | 35 (7) | 35 (6) | 0.57 |
| White blood cell count (1000 cells/mm3) | 12.4 (5.9) | 12.1 (5.7) | 13.0 (6.2) | 0.26 |
| Platelets (100 cells/mm3) | 220 (95) | 230 (94) | 201 (95) | 0.023 |
| Interleukin-6 (pg/mL, N=44) | 249 (409) | 286 (491) | 177 (84) | 0.5 |
| Ferritin (ng/mL) | 3177 (8738) | 1752 (4881) | 5687 (12649) | 0.003 |
| Fibrinogen (mg/dL, N=105) | 614 (171) | 643 (152) | 554 (194) | 0.011 |
| D-dimer (mcg/mL) | 4.8 (8.1) | 4.4 (7.3) | 5.5 (9.3) | 0.37 |
| C-reactive protein (mg/dL) | 63.3 (101) | 60.5 (92) | 68.3 (117) | 0.6 |
| Troponin T (ng/L) | 65.3 (12.2) | 43.8 (8.3) | 92.1 (154.6) | 0.037 |
| Troponin I (ng/L) | 692 (2373) | 371 (1524) | 1512 (3660) | 0.007 |
Data shown as mean for continuous variables and percent for categorical variables, using multiple imputed data.