Table 3:
Characteristics of intubated COVID-19 patients compared to patients with ARDS secondary to pneumonia.
| ARDS | COVID-19 | P | |
|---|---|---|---|
| Number | 506 | 243 | |
| Age (y) | 50.2 (14.9) | 62.8 (14.9) | <0.001 |
| Female sex (%) | 51.3 | 39.0 | 0.0017 |
| African-American race (%) | 21.7 | 35.3 | 0.001 |
| Temperature (C) | 37.5 (1.0) | 38.2 (1.1) | <0.001 |
| Heart rate (beats per minute) | 101 (20) | 113 (21) | <0.001 |
| Systolic BP (mmHg) | 112 (20) | 84 (15) | <0.001 |
| Diastolic BP (mmHg) | 59 (12) | 47 (9) | <0.001 |
| Vasopressor use (%) | 28.1 | 87.2 | <0.001 |
| Weight (kg) | 77.5 (19.9) | 87.5 (27.2) | <0.001 |
| Body-mass index (kg/m2) | 27.2 (7.0) | 30.9 (8.3) | <0.001 |
| Tidal volume (mL) | 469 (106) | 414 (66) | <0.001 |
| Positive end-expiratory pressure (cm H2O) | 9.6 (3.9) | 12.4 (4.3) | <0.001 |
| Plateau pressure (cm H2O) | 26.5 (7.0) | 27.2 (18.6) | 0.58 |
| PaO2/FIO2 ratio | 143 (64) | 99 (75) | <0.001 |
| Lung compliance (mL/cm H2O) | 32.3 (18.3) | 30.6 (15.4) | 0.29 |
| pH | 7.36 (0.1) | 7.3 (0.11) | <0.001 |
| pCO2 (mmHg) | 40.3 (10.8) | 49.5 (14.2) | <0.001 |
| Creatinine (mg/dL) | 1.4 (1.4) | 2.2 (2.8) | <0.001 |
| Bilirubin (mg/dL) | 1.1 (1.5) | 0.7 (0.5) | 0.002 |
| White blood cell count (1000 cells/mm3) | 14.1 (8.4) | 12.4 (5.9) | 0.005 |
| Troponin positive (%) | 49.6 | 51.0 | 0.72 |
| Troponin category (%) | 0.37 | ||
| <ULN | 50.4 | 49.0 | |
| 1–5x ULN | 24.1 | 22.6 | |
| 5–10x ULN | 8.3 | 12.4 | |
| >10xULN | 17.2 | 16.1 | |
| Death (%) | 26.5 | 36.2 | 0.007 |
| Ventilator-free days (days) | 13.1 (9.9) | 13.0 (10.4) | 0.85 |
Data shown as mean for continuous variables and percent for categorical variables, using multiple imputed data.