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. Author manuscript; available in PMC: 2021 Aug 6.
Published in final edited form as: Parasitology. 2021 Feb 17;148(10):1143–1150. doi: 10.1017/S0031182021000317

Fig. 4.

Fig. 4.

GSH1 overexpression effects during antitrypanosomal drug treatments. Comparison of parental cell line (grey) and GSH1 overexpressing cell line (green) during antitrypanosomal drug treatments for 24 h in vitro at the concentrations indicated for their effects on: (A) cell cycle, (B) DNA synthesis by BrdU incorporation assay, and (D) growth inhibition, statistical significance is shown as Not Significant (N.S or *P < 0.03 and **P < 0.002). (C) Evaluation of fexinidazole effects on DNA synthesis over biological triplicates (left graph) and at additional drug concentrations.