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. Author manuscript; available in PMC: 2007 Apr 24.
Published in final edited form as: J Neurosci. 2006 Jul 19;26(29):7707–7717. doi: 10.1523/JNEUROSCI.1977-06.2006

Figure 7.

Figure 7

Whole-cell recordings from an olfactory receptor cell, illustrating the effect of tetrodotoxin (TTX) on the inward current in a cell that responds to NPY. A, Currents elicited by stepping from a holding potential of -60 mV to a series of voltage pulses ranging from −100 mV to +100 mV, in 10 mV increments. These currents were recorded in barium-APS, 3 min before NPY was applied to the cell. B, Currents elicited after 5 min exposure to a bath solution containing 100 nM NPY. The peak magnitude of the inward current is approximately 12% larger than in A. C, Currents elicited after 5 min exposure to 100 nM NPY + 100 nM TTX. Note that the large, rapidly-inactivating, voltage-activated inward current that is probably carried by sodium has been blocked; the inward current is approximately 25% of its initial magnitude. D, Currents elicited after 12.5 min of washing in barium-APS. The inward current has returned to 97% of its initial magnitude.