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. Author manuscript; available in PMC: 2021 Mar 24.
Published in final edited form as: Epigenomes. 2020 Dec 11;4(4):28. doi: 10.3390/epigenomes4040028

Table 1.

Selected characteristics of study sample comparing vegans, pesco vegetarians, and omnivores.

Demographic and Lifestyle n = 38 n = 41 n = 68 Vegan vs. Omni Pesco vs. Omni Vegan vs. Pesco
Males (%)
Age at collection, mean ± SD (years) 52.63 48.78 47.06 0.58 0.86 0.73
BMI at collection, mean ± SD 67.78 (8.50) 69.93 (7.87) 66.42 (6.73) 0.37 0.02 0.25
Exercise, mean ± SD (min/week) 23.62 (4.23) 25.36 (3.63) 27.07 (3.69) <0.0001 0.02 0.05
Sleep hours, mean ± SD (hrs/day) 152.93 (109.59) 76.68 (86.64) 69.23 (95.72) 0.0001 0.58 0.002
Perception of one’s own health (%) 7.30 (0.81) 7.03 (0.95) 6.94 (0.93) 0.05 0.65 0.18
 Excellent 0.07 0.82 0.22
 Good 25.71 22.50 17.65
 Fair 54.29 70.00 75.00
Prevalent cancer (%) 20.00 7.50 7.35
 Yes 0.57 0.66 0.91
 No 10.53 9.76 7.35
CVD comorbidities (%) 89.47 90.24 92.65
 None 0.35 0.74 0.57
 1 or more 76.32 70.73 67.65
Cigarette smoke (%) 23.68 29.27 32.35
 Never 0.05 0.51 0.02
 Ever 97.37 80.49 85.29
2.63 19.51 14.71
Dietary intake, mean ± SD
Energy (kcal/d)
Carbohydrate (% of kcal) 1769.82 (585.13) 2029.3 (609.7) 1927.77 (667.22) 0.23 0.43 0.06
Fat (% of kcal) 57.58 (6.96) 52.83 (7.17) 49.74 (8.13) <0.0001 0.05 0.004
Protein (% of kcal) 28.72 (6.92) 33.20 (7.29) 35.66 (7.85) <0.0001 0.11 0.007
Vegetable protein (% of protein) 13.70 (2.80) 13.97 (2.42) 14.61 (2.21) 0.071 0.07 0.65
Animal protein (% of protein) 96.87 (2.57) 80.39 (12.56) 60.63 (14.82) <0.0001 <0.0001 <0.0001
Essential amino acids 3.89 (2.33) 19.92 (12.41) 39.41 (14.75) <0.0001 <0.0001 <0.0001
Leucine (% of protein)
Valine (% of protein) 6.98 (0.48) 7.40 (0.35) 7.61 (0.36) <0.0001 0.003 <0.0001
Isoleucine (% of protein) 4.66 (0.25) 4.89 (0.21) 4.98 (0.21) <0.0001 0.03 <0.0001
Histidine (% of protein) 3.95 (0.24) 4.12 (0.20) 4.29 (0.19) <0.0001 <0.0001 0.0007
Methionine (% of protein) 2.42 (0.13) 2.45 (0.08) 2.54 (0.1) <0.0001 <0.0001 0.24
Tryptophan (% of protein) 1.50 (0.12) 1.73 (0.17) 1.92 (0.16) <0.0001 <0.0001 <0.0001
Threonine (% of protein) 1.26 (0.07) 1.23 (0.06) 1.22 (0.06) 0.002 0.16 0.1
Lysine (% of protein) 3.5 (0.26) 3.47 (0.20) 3.55 (0.17) 0.33 0.04 0.54
Phenylalanine (% of protein) 4.47 (0.48) 4.93 (0.48) 5.55 (0.64) <0.0001 <0.0001 <0.0001
Non-essential amino acids 4.88 (0.24) 4.88 (0.11) 4.75 (0.16) 0.005 <0.0001 0.99
Glutamate (% of protein)
Aspartate (% of protein) 23.07 (1.94) 22.82 (1.58) 22.18 (1.64) 0.010 0.05 0.53
Alanine (% of protein) 10.20 (1.33) 9.50 (0.79) 9.07 (0.71) <0.0001 0.004 0.005
Cysteine (% of protein) 4.40 (0.38) 4.25 (0.27) 4.29 (0.23) 0.06 0.46 0.05
Arginine (% of protein) 1.61 (0.14) 1.65 (0.16) 1.65 (0.16) 0.21 0.95 0.28
Tyrosine (% of protein) 6.79 (0.79) 6.12 (0.73) 5.61 (0.66) <0.0001 0.0003 0.0002
Glycine (% of protein) 3.04 (0.28) 3.24 (0.25) 3.38 (0.20) <0.0001 0.002 0.001
Proline (% of protein) 4.27 (0.31) 3.92 (0.34) 3.79 (0.32) <0.0001 0.05 <0.0001
Serine (% of protein) 6.65 (0.92) 7.24 (0.86) 7.31 (0.73) <0.0001 0.64 0.004
Micronutrients 4.87 (0.29) 4.95 (0.16) 4.79 (0.19) 0.10 <0.0001 0.12
Vitamin B2, mg/1000 kcal
Vitamin B6, mg/1000 kcal 2.85 (3.28) 3.64 (5.18) 2.78 (6.62) 0.95 0.43 0.42
Vitamin B-12, mcg/1000 kcal 3.56 (7.04) 8.54 (15.42) 5.14 (10.21) 0.4 0.17 0.07
Folate, mcg/1000 kcal 3.93 (4.43) 7.64 (9.38) 6.19 (11.23) 0.24 0.49 0.03
Choline, mg/1000 kcal 460.0 (387.8) 440.1 (193.0) 401.9 (214.1) 0.19 0.35 0.67
Betaine, mg/1000 kcal 117.0 (21.73) 122.9 (29.40) 136.9 (27.61) 0.0002 0.01 0.32
0.91 0.6